Suppressor of cytokine signaling proteins
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:SOCS_proteins
|
| gptkbp:discoveredBy |
1997
|
| gptkbp:domain |
gptkb:SOCS_box
SH2 domain |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:function |
negative regulation of cytokine signaling
|
| gptkbp:hasMember |
gptkb:SOCS1
gptkb:SOCS2 gptkb:SOCS3 gptkb:SOCS4 gptkb:SOCS5 gptkb:SOCS6 gptkb:SOCS7 CIS (cytokine-inducible SH2-containing protein) |
| https://www.w3.org/2000/01/rdf-schema#label |
Suppressor of cytokine signaling proteins
|
| gptkbp:orthologIn |
gptkb:fish
birds mammals |
| gptkbp:proteinFamily |
gptkb:SOCS_gene_family
|
| gptkbp:regulates |
gptkb:JAK-STAT_signaling_pathway
apoptosis cell growth immune response |
| gptkbp:role |
gptkb:cancer
autoimmune diseases inflammatory diseases |
| gptkbp:bfsParent |
gptkb:SOCS_box
|
| gptkbp:bfsLayer |
7
|