|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:5-HTT
gptkb:SERT
gptkb:solute_carrier_family_6_member_4
|
|
gptkbp:associatedWith
|
gptkb:depression
gptkb:autism_spectrum_disorder
gptkb:obsessive-compulsive_disorder
gptkb:major_depressive_disorder
anxiety
mood regulation
|
|
gptkbp:encodes
|
gptkb:serotonin_transporter
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSMUSG00000015568
20534
|
|
gptkbp:expressedIn
|
gptkb:placenta
brain
intestine
|
|
gptkbp:function
|
serotonin reuptake
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
serotonin:sodium symporter activity
integral component of plasma membrane
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Slc6a4
|
|
gptkbp:locatedOnChromosome
|
11
|
|
gptkbp:mutationAssociatedWith
|
altered serotonin uptake
|
|
gptkbp:orthologIn
|
gptkb:SLC6A4_(human)
|
|
gptkbp:pathway
|
neurotransmitter transport
serotonergic synapse
|
|
gptkbp:pharmacological_target
|
gptkb:tricyclic_antidepressants
gptkb:SSRIs
gptkb:MDMA
cocaine
|
|
gptkbp:product
|
gptkb:SERT_protein
|
|
gptkbp:regulates
|
transcriptional regulation
epigenetic modification
target of SSRIs
|
|
gptkbp:species
|
gptkb:Mus_musculus
|
|
gptkbp:UniProtID
|
gptkb:P31645_(mouse)
|
|
gptkbp:bfsParent
|
gptkb:ENSG00000133703
|
|
gptkbp:bfsLayer
|
6
|