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gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:5-HTT
gptkb:solute_carrier_family_6_member_4
|
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gptkbp:associatedWith
|
gptkb:depression
gptkb:autism_spectrum_disorder
gptkb:obsessive-compulsive_disorder
anxiety disorders
|
|
gptkbp:encodedBy
|
gptkb:SLC6A4
|
|
gptkbp:foundIn
|
gptkb:placenta
central nervous system
platelets
|
|
gptkbp:fullName
|
gptkb:serotonin_transporter
|
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gptkbp:function
|
transports serotonin from synaptic cleft to presynaptic neuron
|
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gptkbp:gene
|
gptkb:SLC6A4
|
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gptkbp:hasPolymorphism
|
gptkb:5-HTTLPR
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SERT
|
|
gptkbp:inhibitedBy
|
gptkb:tricyclic_antidepressants
gptkb:MDMA
gptkb:selective_serotonin_reuptake_inhibitors
cocaine
|
|
gptkbp:locatedOnChromosome
|
gptkb:17q11.2
|
|
gptkbp:location
|
presynaptic neuron membrane
|
|
gptkbp:memberOf
|
gptkb:solute_carrier_family_6
|
|
gptkbp:regulates
|
phosphorylation
protein-protein interactions
genetic polymorphisms
|
|
gptkbp:species
|
gptkb:human
gptkb:mouse
gptkb:zebrafish
right
|
|
gptkbp:structure
|
12 transmembrane domains
|
|
gptkbp:bfsParent
|
gptkb:ENSG00000105851
gptkb:ENSG00000133703
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gptkbp:bfsLayer
|
6
|