Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alias |
gptkb:SHC1
SHC-transforming protein Src homology 2 domain-containing |
| gptkbp:alternativeSplicing |
gptkb:p46Shc
gptkb:p52Shc gptkb:p66Shc |
| gptkbp:binds |
phosphotyrosine-containing proteins
|
| gptkbp:discoveredIn |
1992
|
| gptkbp:domain |
SH2 domain
PTB domain CH1 domain |
| gptkbp:encodedBy |
gptkb:SHC1_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
signal transduction
|
| https://www.w3.org/2000/01/rdf-schema#label |
Shc protein
|
| gptkbp:involvedIn |
gptkb:MAPK/ERK_pathway
apoptosis cell growth |
| gptkbp:locale |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:phosphorylates |
gptkb:receptor_tyrosine_kinases
|
| gptkbp:regulates |
cellular senescence
oxidative stress response |
| gptkbp:UniProtID |
gptkb:P29353
|
| gptkbp:bfsParent |
gptkb:GRB2_protein
|
| gptkbp:bfsLayer |
7
|