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gptkbp:instanceOf
|
Cell
|
|
gptkbp:alsoKnownAs
|
gptkb:nurse_cells
|
|
gptkbp:discoveredBy
|
gptkb:Enrico_Sertoli
|
|
gptkbp:expressedIn
|
gptkb:androgen_receptor
gptkb:FSH_receptor
|
|
gptkbp:form
|
tight junctions
|
|
gptkbp:foundIn
|
gptkb:testis
|
|
gptkbp:function
|
form blood-testis barrier
nourish developing sperm cells
phagocytose residual cytoplasm
secrete androgen-binding protein
secrete anti-Müllerian hormone
secrete inhibin
support spermatogenesis
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Sertoli cells
|
|
gptkbp:involvedIn
|
male sex differentiation
testicular development
testicular immune privilege
|
|
gptkbp:locatedIn
|
gptkb:seminiferous_tubules
|
|
gptkbp:medium
|
spermiation
|
|
gptkbp:number
|
limits sperm production
|
|
gptkbp:origin
|
gptkb:embryonic_gonadal_ridge
|
|
gptkbp:phagocytose
|
apoptotic germ cells
|
|
gptkbp:presentIn
|
mammals
vertebrates
|
|
gptkbp:proliferate
|
during fetal development
|
|
gptkbp:regulates
|
gptkb:spermatogonial_stem_cell_niche
gptkb:testicular_microenvironment
germ cell movement
hormonal feedback
|
|
gptkbp:response
|
gptkb:follicle-stimulating_hormone
testosterone
|
|
gptkbp:secretes
|
gptkb:estradiol
gptkb:glial_cell_line-derived_neurotrophic_factor
gptkb:interleukin-1
gptkb:activin
gptkb:ceruloplasmin
gptkb:clusterin
gptkb:plasminogen_activator
gptkb:stem_cell_factor
gptkb:testicular_inhibin_B
gptkb:transferrin
growth factors
lactate
testicular fluid
|
|
gptkbp:stopProliferation
|
at puberty
|
|
gptkbp:supports
|
gptkb:germ_cells
spermatid maturation
|
|
gptkbp:bfsParent
|
gptkb:testis
|
|
gptkbp:bfsLayer
|
5
|