Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
copper oxidase
ferroxidase |
| gptkbp:contains |
copper
|
| gptkbp:discoveredBy |
Holmberg and Laurell
|
| gptkbp:discoveredIn |
1941
|
| gptkbp:EC_number |
1.16.3.1
|
| gptkbp:encodedBy |
CP gene
|
| gptkbp:foundIn |
human blood plasma
|
| gptkbp:function |
copper transport
ferroxidase activity |
| gptkbp:glycosylation |
yes
|
| gptkbp:halfLife |
5.5 days
|
| https://www.w3.org/2000/01/rdf-schema#label |
ceruloplasmin
|
| gptkbp:locatedOnChromosome |
3q24-q25
|
| gptkbp:measures |
immunoassay
|
| gptkbp:molecularWeight |
~132 kDa
|
| gptkbp:numberOfCopperAtoms |
6–7
|
| gptkbp:OMIM |
117700
|
| gptkbp:PDB |
1KCW
|
| gptkbp:presentIn |
vertebrates
|
| gptkbp:range |
20–40 mg/dL (adults)
|
| gptkbp:role |
antioxidant defense
iron metabolism |
| gptkbp:significance |
high in inflammation
low in Menkes disease low in Wilson's disease |
| gptkbp:structure |
single polypeptide chain
|
| gptkbp:synthesisType |
liver
|
| gptkbp:UniProtID |
P00450
|
| gptkbp:bfsParent |
gptkb:Sertoli_cells
|
| gptkbp:bfsLayer |
6
|