STI-571

URI: https://gptkb.org/entity/STI-571

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:drug
gptkbp:administeredBy	oral
gptkbp:alsoKnownAs	gptkb:Gleevec gptkb:imatinib
gptkbp:approvalYear	2001
gptkbp:approvedBy	gptkb:FDA
gptkbp:ATCCode	L01XE01
gptkbp:category	gptkb:protease_inhibitor gptkb:antineoplastic_agent
gptkbp:chemicalFormula	C29H31N7O
gptkbp:developedBy	gptkb:Novartis
gptkbp:discoveredBy	gptkb:Brian_Druker gptkb:Nicholas_Lydon
gptkbp:legalStatus	prescription only
gptkbp:mechanismOfAction	gptkb:receptor_tyrosine_kinase
gptkbp:patent	gptkb:US5521184A
gptkbp:sideEffect	nausea edema fatigue rash muscle cramps
gptkbp:target	gptkb:BCR-ABL gptkb:PDGFR gptkb:c-KIT
gptkbp:usedFor	gptkb:gastrointestinal_stromal_tumor gptkb:leukemia gptkb:chronic_myeloid_leukemia
gptkbp:bfsParent	gptkb:CHEMBL958 gptkb:CHEMBL472
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	STI-571