STI-571

URI: https://gptkb.org/entity/STI-571
GPTKB entity
Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkbp:administeredBy oral
gptkbp:alsoKnownAs gptkb:Gleevec
gptkb:imatinib
gptkbp:approvalYear 2001
gptkbp:approvedBy gptkb:FDA
gptkbp:ATCCode L01XE01
gptkbp:category gptkb:protease_inhibitor
gptkb:antineoplastic_agent
gptkbp:chemicalFormula C29H31N7O
gptkbp:developedBy gptkb:Novartis
gptkbp:discoveredBy gptkb:Brian_Druker
gptkb:Nicholas_Lydon
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction gptkb:receptor_tyrosine_kinase
gptkbp:patent gptkb:US5521184A
gptkbp:sideEffect nausea
edema
fatigue
rash
muscle cramps
gptkbp:target gptkb:BCR-ABL
gptkb:PDGFR
gptkb:c-KIT
gptkbp:usedFor gptkb:gastrointestinal_stromal_tumor
gptkb:leukemia
gptkb:chronic_myeloid_leukemia
gptkbp:bfsParent gptkb:CHEMBL958
gptkb:CHEMBL472
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label STI-571