STAT family

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy cytokines
growth factors
gptkbp:associatedWith gptkb:cancer
immunodeficiency
autoimmune disease
gptkbp:discoveredBy gptkb:James_E._Darnell
gptkbp:domain SH2 domain
DNA-binding domain
transactivation domain
gptkbp:firstDescribed 1994
gptkbp:foundIn vertebrates
gptkbp:fullName Signal Transducer and Activator of Transcription family
gptkbp:function signal transduction
transcription factor
gptkbp:GO_term GO:0007165
GO:0003700
https://www.w3.org/2000/01/rdf-schema#label STAT family
gptkbp:involvedIn gptkb:JAK-STAT_signaling_pathway
gptkbp:member gptkb:STAT1
gptkb:STAT2
gptkb:STAT4
gptkb:STAT5A
gptkb:STAT5B
gptkb:STAT6
gptkb:STAT3
gptkbp:role apoptosis
differentiation
cell growth
immune response
gptkbp:bfsParent gptkb:STAT5
gptkbp:bfsLayer 8