|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
immunodeficiency
|
|
gptkbp:discoveredBy
|
gptkb:Darnell_Lab
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:encodedBy
|
gptkb:STAT2_gene
|
|
gptkbp:Entrez_Gene_ID
|
6773
|
|
gptkbp:formsComplexWith
|
gptkb:STAT1
gptkb:IRF9
|
|
gptkbp:formsISGF3Complex
|
yes
|
|
gptkbp:fullName
|
gptkb:Signal_transducer_and_activator_of_transcription_2
|
|
gptkbp:function
|
transcription factor
mediates interferon signaling
|
|
gptkbp:gene
|
gptkb:STAT2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
STAT2
|
|
gptkbp:involvedIn
|
gptkb:JAK-STAT_signaling_pathway
type I interferon signaling
|
|
gptkbp:locatedOnChromosome
|
12q13.3
|
|
gptkbp:molecularWeight
|
113 kDa
|
|
gptkbp:mutationAssociatedWith
|
increased susceptibility to viral infection
|
|
gptkbp:OMIM
|
600556
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Stat2
|
|
gptkbp:phosphorylates
|
Tyr690
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
P52630
|
|
gptkbp:bfsParent
|
gptkb:JAK-STAT_signaling_pathway
gptkb:STAT_pathway
gptkb:STATs
gptkb:STAT1
gptkb:STAT_proteins
gptkb:JAK-STAT_pathway
gptkb:JAK/STAT_signaling_pathway
|
|
gptkbp:bfsLayer
|
7
|