STAT2

URI: https://gptkb.org/entity/STAT2

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeSplicing	yes
gptkbp:associatedWith	gptkb:immunodeficiency
gptkbp:discoveredBy	gptkb:Darnell_Lab
gptkbp:discoveredIn	1993
gptkbp:encodedBy	gptkb:STAT2_gene
gptkbp:Entrez_Gene_ID	6773
gptkbp:formsComplexWith	gptkb:STAT1 gptkb:IRF9
gptkbp:formsISGF3Complex	yes
gptkbp:fullName	gptkb:Signal_transducer_and_activator_of_transcription_2
gptkbp:function	gptkb:transcription_factor mediates interferon signaling
gptkbp:gene	gptkb:STAT2
gptkbp:involvedIn	gptkb:JAK-STAT_signaling_pathway type I interferon signaling
gptkbp:locatedOnChromosome	12q13.3
gptkbp:molecularWeight	113 kDa
gptkbp:mutationAssociatedWith	increased susceptibility to viral infection
gptkbp:OMIM	600556
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:orthologInMouse	gptkb:Stat2
gptkbp:phosphorylates	Tyr690
gptkbp:subcellularLocation	gptkb:nucleus gptkb:cytoplasm
gptkbp:UniProtID	P52630
gptkbp:bfsParent	gptkb:JAK-STAT_signaling_pathway gptkb:STAT_pathway gptkb:STATs gptkb:STAT1
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	STAT2