STAT2

URI: https://gptkb.org/entity/STAT2
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeSplicing yes
gptkbp:associatedWith gptkb:immunodeficiency
gptkbp:discoveredBy gptkb:Darnell_Lab
gptkbp:discoveredIn 1993
gptkbp:encodedBy gptkb:STAT2_gene
gptkbp:Entrez_Gene_ID 6773
gptkbp:formsComplexWith gptkb:STAT1
gptkb:IRF9
gptkbp:formsISGF3Complex yes
gptkbp:fullName gptkb:Signal_transducer_and_activator_of_transcription_2
gptkbp:function gptkb:transcription_factor
mediates interferon signaling
gptkbp:gene gptkb:STAT2
gptkbp:involvedIn gptkb:JAK-STAT_signaling_pathway
type I interferon signaling
gptkbp:locatedOnChromosome 12q13.3
gptkbp:molecularWeight 113 kDa
gptkbp:mutationAssociatedWith increased susceptibility to viral infection
gptkbp:OMIM 600556
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse gptkb:Stat2
gptkbp:phosphorylates Tyr690
gptkbp:subcellularLocation gptkb:nucleus
gptkb:cytoplasm
gptkbp:UniProtID P52630
gptkbp:bfsParent gptkb:JAK-STAT_signaling_pathway
gptkb:STAT_pathway
gptkb:STATs
gptkb:STAT1
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label STAT2