Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:Son_of_sevenless_homolog_1
gptkb:SOS-1 |
| gptkbp:domain |
gptkb:Dbl_homology_domain
gptkb:pleckstrin_homology_domain proline-rich region |
| gptkbp:encodedBy |
gptkb:SOS1_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
guanine nucleotide exchange factor
|
| https://www.w3.org/2000/01/rdf-schema#label |
SOS1 protein
|
| gptkbp:interactsWith |
gptkb:EGFR
gptkb:GRB2 gptkb:RAS_protein |
| gptkbp:involvedIn |
gptkb:RAS_signaling_pathway
|
| gptkbp:locale |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:locatedOnChromosome |
2p22-p16
|
| gptkbp:molecularWeight |
~155 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:hereditary_gingival_fibromatosis
gptkb:Noonan_syndrome |
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster |
| gptkbp:postTranslationalModification |
phosphorylation
|
| gptkbp:regulates |
RAS GTPase activity
|
| gptkbp:structure |
multi-domain protein
|
| gptkbp:UniProtID |
Q07889
|
| gptkbp:bfsParent |
gptkb:SOS1
|
| gptkbp:bfsLayer |
6
|