Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:catalyzes |
exchange of GDP for GTP
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:domain |
gptkb:PH_domain
gptkb:Sec7_domain CDC25 domain DH domain |
| gptkbp:example |
gptkb:Dbl_family_proteins
gptkb:RCC1 gptkb:RasGRF gptkb:eIF2B gptkb:Vav gptkb:SOS1 |
| gptkbp:foundIn |
eukaryotic cells
|
| gptkbp:function |
activates small GTPases
|
| https://www.w3.org/2000/01/rdf-schema#label |
GEF
|
| gptkbp:interactsWith |
GDP-bound GTPases
|
| gptkbp:involvedIn |
vesicle trafficking
cell signaling regulation of cytoskeleton |
| gptkbp:opposedBy |
gptkb:GTPase-activating_protein_(GAP)
|
| gptkbp:regulates |
gptkb:Ran_family_GTPases
Arf family GTPases Rab family GTPases Ras family GTPases Rho family GTPases |
| gptkbp:relatedTo |
cancer research
immunology neurobiology |
| gptkbp:standsFor |
gptkb:Guanine_nucleotide_Exchange_Factor
|
| gptkbp:bfsParent |
gptkb:Global_Environment_Facility
gptkb:UNEP_Global_Environment_Facility |
| gptkbp:bfsLayer |
5
|