|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:EC_1.2.1.12
gptkb:Peptidyl-cysteine_S-nitrosylase_GAPDH
gptkb:GAPDH
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cancer
|
|
gptkbp:encodedBy
|
gptkb:GAPDH
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSP00000374867
|
|
gptkbp:enzymeCommissionNumber
|
1.2.1.12
|
|
gptkbp:expressedIn
|
ubiquitous
|
|
gptkbp:fullName
|
gptkb:Glyceraldehyde-3-phosphate_dehydrogenase
|
|
gptkbp:function
|
catalyzes the sixth step of glycolysis
|
|
gptkbp:gene
|
gptkb:GAPDH
|
|
gptkbp:GO_term
|
GO:0005737 (cytoplasm)
GO:0006096 (glycolytic process)
GO:0004365 (glyceraldehyde-3-phosphate dehydrogenase activity)
|
|
gptkbp:HGNC_ID
|
4141
|
|
gptkbp:KEGGID
|
gptkb:hsa:2597
|
|
gptkbp:locatedOnChromosome
|
gptkb:12p13.31
|
|
gptkbp:location
|
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
36 kDa
|
|
gptkbp:OMIM
|
138400
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Gapdh
gptkb:rat_Gapdh
gptkb:yeast_TDH1
|
|
gptkbp:pathway
|
glycolysis
gluconeogenesis
|
|
gptkbp:PDB
|
gptkb:1ZNQ
gptkb:2V4O
1U8F
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
S-nitrosylation
|
|
gptkbp:Reactome
|
gptkb:R-HSA-70171
|
|
gptkbp:RefSeq
|
gptkb:NP_002037.2
|
|
gptkbp:reviewedBy
|
gptkb:Swiss-Prot
|
|
gptkbp:sequence
|
335 amino acids
|
|
gptkbp:structure
|
contains catalytic domain
contains NAD+ binding domain
|
|
gptkbp:subunit
|
homotetramer
|
|
gptkbp:tissue_specificity
|
expressed in all tissues
|
|
gptkbp:UniProtID
|
gptkb:P29350
|
|
gptkbp:bfsParent
|
gptkb:PTPN6
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P29350
|