Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:PTPN1
|
| gptkbp:associatedWith |
gptkb:cancer
gptkb:type_2_diabetes obesity |
| gptkbp:discoveredBy |
Tonks et al.
|
| gptkbp:discoveredIn |
1988
|
| gptkbp:encodedBy |
PTPN1 gene
|
| gptkbp:enzymeCommissionNumber |
3.1.3.48
|
| gptkbp:function |
gptkb:protein_tyrosine_phosphatase
|
| https://www.w3.org/2000/01/rdf-schema#label |
PTP-1C
|
| gptkbp:involvedIn |
insulin signaling pathway
oncogenic transformation regulation of cell growth regulation of differentiation mitotic cycle |
| gptkbp:locatedOnChromosome |
gptkb:20q13.13
|
| gptkbp:location |
gptkb:endoplasmic_reticulum
gptkb:cytoplasm |
| gptkbp:molecularWeight |
50 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:regulates |
gptkb:insulin_receptor
leptin receptor JAK/STAT signaling |
| gptkbp:structure |
contains PTP domain
contains two SH2 domains |
| gptkbp:UniProtID |
gptkb:P18031
|
| gptkbp:bfsParent |
gptkb:PTPN2
|
| gptkbp:bfsLayer |
7
|