protein tyrosine phosphatase
GPTKB entity
Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:catalyzes |
dephosphorylation of tyrosine residues
|
| gptkbp:discoveredBy |
gptkb:Edwin_G._Krebs
gptkb:Edmond_H._Fischer |
| gptkbp:EC_number |
3.1.3.48
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:hasRole |
gptkb:cancer
gptkb:diabetes neurodegenerative diseases autoimmune diseases |
| https://www.w3.org/2000/01/rdf-schema#label |
protein tyrosine phosphatase
|
| gptkbp:inhibitedBy |
pervanadate
vanadate |
| gptkbp:proteinFamily |
gptkb:PTPN
PTPR |
| gptkbp:regulates |
cell differentiation
metabolism cell growth cell signaling cell cycle |
| gptkbp:relatedTo |
gptkb:protein
|
| gptkbp:structure |
regulatory domain
catalytic domain |
| gptkbp:subclassOf |
non-receptor protein tyrosine phosphatase
receptor-type protein tyrosine phosphatase |
| gptkbp:substrate |
phosphotyrosine-containing proteins
|
| gptkbp:bfsParent |
gptkb:PTPRM
gptkb:tyrosine_phosphatase gptkb:PTPRT gptkb:Ptprf |
| gptkbp:bfsLayer |
7
|