|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
MRP8
calgranulin A
|
|
gptkbp:associatedWith
|
psoriasis
rheumatoid arthritis
cystic fibrosis
inflammatory bowel disease
|
|
gptkbp:binds
|
copper
zinc
calcium
|
|
gptkbp:biomarker_for
|
gptkb:cancer
infection
inflammatory diseases
|
|
gptkbp:encodedBy
|
S100A8 gene
|
|
gptkbp:Entrez_Gene_ID
|
6279
ENSG00000143546
|
|
gptkbp:expressedIn
|
monocytes
neutrophils
|
|
gptkbp:forms_heterodimer
|
calprotectin
|
|
gptkbp:formsComplexWith
|
gptkb:S100A9
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
immune response
inflammatory response
|
|
gptkbp:gene
|
gptkb:S100A8
|
|
gptkbp:HGNC_ID
|
10498
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
S100A8
|
|
gptkbp:inhibitedBy
|
microbial growth
|
|
gptkbp:interactsWith
|
gptkb:TLR4
gptkb:RAGE
|
|
gptkbp:involves
|
oxidative stress response
chemotaxis
antimicrobial activity
regulation of inflammation
|
|
gptkbp:length
|
93
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1q21
|
|
gptkbp:molecularWeight
|
10.8 kDa
|
|
gptkbp:OMIM
|
123464
|
|
gptkbp:PDB
|
1MR8
|
|
gptkbp:postTranslationalModification
|
phosphorylation
oxidation
|
|
gptkbp:proteinFamily
|
gptkb:S100_protein_family
|
|
gptkbp:regulates
|
gptkb:migration
cytoskeleton dynamics
leukocyte adhesion
|
|
gptkbp:released_during
|
inflammation
|
|
gptkbp:structure
|
EF-hand calcium-binding domain
|
|
gptkbp:subcellularLocation
|
gptkb:cytoplasm
extracellular space
|
|
gptkbp:UniProtID
|
P05109
|
|
gptkbp:bfsParent
|
gptkb:chromosome_1q21
gptkb:S-100_protein
gptkb:S100_protein
gptkb:S100_protein_family
gptkb:calgranulin
gptkb:calgranulin_B
|
|
gptkbp:bfsLayer
|
7
|