|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:MRP14
gptkb:calgranulin_B
migration inhibitory factor-related protein 14
|
|
gptkbp:associatedWith
|
gptkb:inflammatory_bowel_disease
rheumatoid arthritis
cystic fibrosis
|
|
gptkbp:encodedBy
|
S100A9 gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000163220
6280
|
|
gptkbp:expressedIn
|
monocytes
neutrophils
|
|
gptkbp:forms_heterodimer
|
calprotectin
|
|
gptkbp:formsComplexWith
|
gptkb:S100A8
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
binds calcium
regulates immune response
antimicrobial activity
involved in inflammatory processes
binds zinc
|
|
gptkbp:gene
|
gptkb:S100A9
|
|
gptkbp:HGNC_ID
|
HGNC:10499
|
|
gptkbp:involves
|
innate immune response
leukocyte migration
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1q21
|
|
gptkbp:molecularWeight
|
13 kDa
|
|
gptkbp:OMIM
|
123885
|
|
gptkbp:PDB
|
1IRJ
|
|
gptkbp:postTranslationalModification
|
phosphorylation
oxidation
|
|
gptkbp:proteinFamily
|
gptkb:S100_protein_family
|
|
gptkbp:regulates
|
inflammatory cytokine production
NADPH oxidase activity
|
|
gptkbp:structure
|
EF-hand calcium-binding domain
|
|
gptkbp:subcellularLocation
|
gptkb:cytoplasm
extracellular space
|
|
gptkbp:UniProtID
|
P06702
|
|
gptkbp:bfsParent
|
gptkb:S-100_protein
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
S100A9
|