S100A9

GPTKB entity

Statements (46)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:MRP14
gptkb:calgranulin_B
migration inhibitory factor-related protein 14
gptkbp:associatedWith rheumatoid arthritis
cystic fibrosis
inflammatory bowel disease
gptkbp:encodedBy S100A9 gene
gptkbp:Entrez_Gene_ID gptkb:ENSG00000163220
6280
gptkbp:expressedIn monocytes
neutrophils
gptkbp:forms_heterodimer calprotectin
gptkbp:formsComplexWith gptkb:S100A8
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function binds calcium
regulates immune response
antimicrobial activity
involved in inflammatory processes
binds zinc
gptkbp:gene gptkb:S100A9
gptkbp:HGNC_ID HGNC:10499
https://www.w3.org/2000/01/rdf-schema#label S100A9
gptkbp:involves innate immune response
leukocyte migration
gptkbp:locatedOnChromosome gptkb:chromosome_1q21
gptkbp:molecularWeight 13 kDa
gptkbp:OMIM 123885
gptkbp:PDB 1IRJ
gptkbp:postTranslationalModification phosphorylation
oxidation
gptkbp:proteinFamily gptkb:S100_protein_family
gptkbp:regulates inflammatory cytokine production
NADPH oxidase activity
gptkbp:structure EF-hand calcium-binding domain
gptkbp:subcellularLocation gptkb:cytoplasm
extracellular space
gptkbp:UniProtID P06702
gptkbp:bfsParent gptkb:chromosome_1q21
gptkb:S-100_protein
gptkb:S100_protein
gptkb:MRP14
gptkb:S100_protein_family
gptkb:calgranulin
gptkb:calgranulin_B
gptkbp:bfsLayer 7