Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abnormalLevelIndicates |
gptkb:Alzheimer's_disease
gptkb:Down_syndrome myocardial infarction inflammatory diseases brain injury |
| gptkbp:discoveredBy |
Brocklehurst et al.
|
| gptkbp:discoveredIn |
1965
|
| gptkbp:foundIn |
gptkb:melanocytes
gptkb:Langerhans_cells gptkb:nervous_system vertebrates glial cells dendritic cells macrophages Schwann cells adipocytes chondrocytes myoepithelial cells |
| gptkbp:function |
apoptosis
regulation of cell cycle regulation of cell differentiation inflammation cell motility regulation of cell growth calcium binding regulation of energy metabolism regulation of protein phosphorylation |
| https://www.w3.org/2000/01/rdf-schema#label |
S-100 protein
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_1q21
|
| gptkbp:marking |
gptkb:Langerhans_cell_histiocytosis
gptkb:schwannoma melanoma glioma certain inflammatory diseases neural tumors |
| gptkbp:molecularWeight |
10-12 kDa
|
| gptkbp:namedAfter |
solubility in 100% saturated ammonium sulfate
|
| gptkbp:solubility |
soluble in 100% saturated ammonium sulfate
|
| gptkbp:structure |
EF-hand calcium-binding motif
|
| gptkbp:subunit |
gptkb:S100B
gptkb:S100A1 gptkb:S100A10 gptkb:S100A11 gptkb:S100A12 gptkb:S100A2 gptkb:S100A4 gptkb:S100A6 gptkb:S100A8 gptkb:S100A9 gptkb:S100P |
| gptkbp:bfsParent |
gptkb:Langerhans_cells
|
| gptkbp:bfsLayer |
6
|