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gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:abnormalLevelIndicates
|
gptkb:Alzheimer's_disease
gptkb:Down_syndrome
myocardial infarction
inflammatory diseases
brain injury
|
|
gptkbp:discoveredBy
|
Brocklehurst et al.
|
|
gptkbp:discoveredIn
|
1965
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gptkbp:foundIn
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gptkb:melanocytes
gptkb:Langerhans_cells
gptkb:nervous_system
vertebrates
glial cells
dendritic cells
macrophages
Schwann cells
adipocytes
chondrocytes
myoepithelial cells
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|
gptkbp:function
|
apoptosis
regulation of cell cycle
regulation of cell differentiation
inflammation
cell motility
regulation of cell growth
calcium binding
regulation of energy metabolism
regulation of protein phosphorylation
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1q21
|
|
gptkbp:marking
|
gptkb:Langerhans_cell_histiocytosis
gptkb:schwannoma
gptkb:glioma
gptkb:melanoma
certain inflammatory diseases
neural tumors
|
|
gptkbp:molecularWeight
|
10-12 kDa
|
|
gptkbp:namedAfter
|
solubility in 100% saturated ammonium sulfate
|
|
gptkbp:solubility
|
soluble in 100% saturated ammonium sulfate
|
|
gptkbp:structure
|
EF-hand calcium-binding motif
|
|
gptkbp:subunit
|
gptkb:S100B
gptkb:S100A1
gptkb:S100A10
gptkb:S100A11
gptkb:S100A12
gptkb:S100A2
gptkb:S100A4
gptkb:S100A6
gptkb:S100A8
gptkb:S100A9
gptkb:S100P
|
|
gptkbp:bfsParent
|
gptkb:Langerhans_cells
|
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gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
S-100 protein
|