Rap guanine nucleotide exchange factor 1
GPTKB entity
Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:Rap1
gptkb:Rap2 |
| gptkbp:alsoKnownAs |
gptkb:C3G
|
| gptkbp:associatedWith |
gptkb:acute_myeloid_leukemia
|
| gptkbp:domain |
gptkb:PH_domain
CDC25-homology domain SH3-binding motif |
| gptkbp:encodedBy |
RAPGEF1 gene
|
| gptkbp:Entrez_Gene_ID |
ENSG00000175197
|
| gptkbp:function |
guanine nucleotide exchange factor
|
| gptkbp:gene |
gptkb:RAPGEF1
|
| https://www.w3.org/2000/01/rdf-schema#label |
Rap guanine nucleotide exchange factor 1
|
| gptkbp:interactsWith |
gptkb:Crk
gptkb:Grb2 gptkb:E-cadherin |
| gptkbp:involves |
cell proliferation
signal transduction cell adhesion |
| gptkbp:locatedOnChromosome |
9q34.3
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
140 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:phosphorylates |
gptkb:Src_family_kinases
|
| gptkbp:RefSeq |
NM_005465
|
| gptkbp:relatedTo |
neuronal differentiation
hematopoiesis |
| gptkbp:UniProtID |
Q13905
|
| gptkbp:bfsParent |
gptkb:RAPGEF1
|
| gptkbp:bfsLayer |
6
|