Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alternativeName |
Exchange Protein Directly Activated by cAMP 2
RAP guanine nucleotide exchange factor 6 |
| gptkbp:associatedWith |
insulin secretion
neuronal signaling |
| gptkbp:discoveredIn |
2001
|
| gptkbp:domain |
Ras-GEF domain
cAMP-binding domain |
| gptkbp:encodedBy |
RAPGEF6 gene
|
| gptkbp:expressedIn |
brain
pancreas |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
cAMP-regulated guanine nucleotide exchange factor
activates Rap1 and Rap2 GTPases |
| https://www.w3.org/2000/01/rdf-schema#label |
EPAC2
|
| gptkbp:locatedOnChromosome |
2q31.1
|
| gptkbp:location |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:molecularWeight |
~115 kDa
|
| gptkbp:UniProtID |
Q8WZA2
|
| gptkbp:bfsParent |
gptkb:RAP1A
|
| gptkbp:bfsLayer |
6
|