|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:RAP1B,_member_of_RAS_oncogene_family
gptkb:RAP1B_protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
thrombosis
vascular disorders
|
|
gptkbp:EC_number
|
3.6.5.2
|
|
gptkbp:encodedBy
|
gptkb:RAP1B_gene
|
|
gptkbp:Entrez_Gene_ID
|
5908
ENSG00000127314
|
|
gptkbp:expressedIn
|
various tissues
platelets
endothelial cells
|
|
gptkbp:function
|
signal transduction
GTPase activity
|
|
gptkbp:gene
|
gptkb:RAP1B
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasGeneCardsID
|
gptkb:RAP1B
|
|
gptkbp:hasPfamID
|
gptkb:PF00071
|
|
gptkbp:hasRefSeqID
|
NM_002885
|
|
gptkbp:HGNC_ID
|
9862
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RAP1B
|
|
gptkbp:interactsWith
|
gptkb:RAPGEF2
gptkb:RAPGEF6
gptkb:KRIT1
gptkb:RAP1GAP
gptkb:RIAM
|
|
gptkbp:InterPro
|
gptkb:IPR001806
|
|
gptkbp:involvedIn
|
cell adhesion
cell junction formation
platelet activation
|
|
gptkbp:KEGGID
|
hsa:5908
|
|
gptkbp:locatedOnChromosome
|
12q21.1
|
|
gptkbp:memberOf
|
Ras-related protein family
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:OMIM
|
179530
|
|
gptkbp:orthologInMouse
|
gptkb:Rap1b
|
|
gptkbp:PDB
|
gptkb:1GUA
|
|
gptkbp:Reactome
|
R-HSA-418594
|
|
gptkbp:regulates
|
cell proliferation
cell migration
cell polarity
integrin-mediated cell adhesion
vascular endothelial growth factor signaling
|
|
gptkbp:UniProtID
|
P61224
|
|
gptkbp:bfsParent
|
gptkb:Ras_gene_family
|
|
gptkbp:bfsLayer
|
5
|