Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:gene
|
gptkbp:alternativeName |
gptkb:EPAC2
gptkb:cAMP-regulated_guanine_nucleotide_exchange_factor_II |
gptkbp:associatedWith |
gptkb:type_2_diabetes
cognitive function |
gptkbp:domain |
Ras-GEF domain
cAMP-binding domain |
gptkbp:encodes |
gptkb:Rap_guanine_nucleotide_exchange_factor_4
|
gptkbp:Entrez_Gene_ID |
11069
ENSG00000115935 |
gptkbp:expressedIn |
brain
pancreas |
gptkbp:function |
acts as a guanine nucleotide exchange factor for Rap1 and Rap2
mediates cAMP signaling |
gptkbp:geneType |
protein-coding
|
gptkbp:HGNC_ID |
gptkb:HGNC:30257
|
https://www.w3.org/2000/01/rdf-schema#label |
RAPGEF4
|
gptkbp:length |
1010 amino acids
|
gptkbp:locatedOnChromosome |
chromosome 2
|
gptkbp:OMIM |
605525
|
gptkbp:orthologInMouse |
gptkb:Rapgef4
|
gptkbp:species |
gptkb:Homo_sapiens
|
gptkbp:subcellularLocation |
gptkb:cell_membrane
gptkb:cytoplasm |
gptkbp:UniProtID |
O43374
|
gptkbp:bfsParent |
gptkb:RAP1A
gptkb:Ras_family |
gptkbp:bfsLayer |
6
|