LGR4

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alternativeName GPR48
leucine-rich repeat-containing G-protein coupled receptor 4
gptkbp:associatedWith gptkb:cancer
stem cell maintenance
developmental processes
gptkbp:chromosomeArm gptkb:11p14.1
gptkbp:encodes LGR4 protein
gptkbp:Entrez_Gene_ID 55366
ENSG00000139292
gptkbp:expressedIn multiple tissues
gptkbp:fullName leucine-rich repeat-containing G-protein coupled receptor 4
gptkbp:function G-protein coupled receptor activity
Wnt signaling pathway regulation
gptkbp:HGNC_ID HGNC:18662
https://www.w3.org/2000/01/rdf-schema#label LGR4
gptkbp:interactsWith gptkb:R-spondin_proteins
gptkbp:locatedOnChromosome 11
gptkbp:mutationAssociatedWith gptkb:bone
congenital anomalies
gptkbp:OMIM 606667
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse Lgr4
gptkbp:proteinFamily leucine-rich repeat domain
7-transmembrane domain
G-protein coupled receptor family
gptkbp:regulates gptkb:Wnt/β-catenin_signaling
cell proliferation
organ development
gptkbp:UniProtID Q9BXB1
gptkbp:bfsParent gptkb:R-spondin
gptkb:R-spondin_proteins
gptkbp:bfsLayer 7