Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:associatedWith |
gptkb:tetra-amelia_syndrome
|
| gptkbp:encodes |
R-spondin-2 protein
|
| gptkbp:Entrez_Gene_ID |
84870
ENSG00000163630 |
| gptkbp:expressedIn |
gptkb:cancer
limb bud various embryonic tissues |
| gptkbp:fullName |
R-spondin 2
|
| gptkbp:function |
activates Wnt/β-catenin signaling pathway
|
| gptkbp:HGNC_ID |
HGNC:24666
|
| https://www.w3.org/2000/01/rdf-schema#label |
RSPO2
|
| gptkbp:interactsWith |
gptkb:LGR4
gptkb:LGR5 gptkb:LGR6 |
| gptkbp:involvedIn |
embryonic development
lung development limb development |
| gptkbp:locatedOnChromosome |
8
8q23.1 |
| gptkbp:mutationAssociatedWith |
congenital limb malformations
|
| gptkbp:OMIM |
610574
|
| gptkbp:orthologIn |
gptkb:mouse
gptkb:zebrafish |
| gptkbp:proteinFamily |
R-spondin family
|
| gptkbp:regulates |
cell differentiation
cell proliferation |
| gptkbp:UniProtID |
Q6UXX9
|
| gptkbp:bfsParent |
gptkb:R-spondin
gptkb:R-spondin_proteins |
| gptkbp:bfsLayer |
7
|