Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activatedBy |
gptkb:receptor_tyrosine_kinases
|
| gptkbp:alternativeName |
gptkb:PLCγ
gptkb:PLC-gamma |
| gptkbp:associatedWith |
autoimmune disorders
immunodeficiency |
| gptkbp:biologicalProcess |
phosphoric diester hydrolase activity
|
| gptkbp:cellularComponent |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:domain |
SH2 domain
SH3 domain |
| gptkbp:EC_number |
3.1.4.11
|
| gptkbp:foundIn |
humans
mammals |
| gptkbp:function |
hydrolyzes phosphatidylinositol 4,5-bisphosphate
|
| gptkbp:gene |
gptkb:PLCG1
gptkb:PLCG2 |
| https://www.w3.org/2000/01/rdf-schema#label |
Phospholipase C gamma
|
| gptkbp:involves |
gptkb:MAPK_signaling_pathway
calcium signaling pathway |
| gptkbp:phosphorylates |
tyrosine kinases
|
| gptkbp:product |
gptkb:inositol_1,4,5-trisphosphate
diacylglycerol |
| gptkbp:role |
cell proliferation
signal transduction immune response |
| gptkbp:subclassOf |
gptkb:phospholipase_C
|
| gptkbp:UniProtID |
P16885 (PLCG2)
P19174 (PLCG1) |
| gptkbp:bfsParent |
gptkb:PLCγ
|
| gptkbp:bfsLayer |
7
|