Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:receptor_tyrosine_kinases
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:cancer
immune disorders |
| gptkbp:domain |
gptkb:PH_domain
SH2 domain SH3 domain |
| gptkbp:encodedBy |
PLCG1 gene
PLCG2 gene |
| gptkbp:fullName |
gptkb:Phospholipase_C_gamma
|
| gptkbp:function |
generates second messengers IP3 and DAG
hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2) |
| https://www.w3.org/2000/01/rdf-schema#label |
PLC-gamma
|
| gptkbp:involvedIn |
signal transduction
|
| gptkbp:phosphorylates |
tyrosine kinases
|
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:subcellularLocation |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:UniProtID |
P16885
P19174 |
| gptkbp:bfsParent |
gptkb:PDGFR-beta
|
| gptkbp:bfsLayer |
7
|