|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:PTPN13
gptkb:FAP-1
gptkb:PTP-BAS
gptkb:PTP1E
|
|
gptkbp:associatedWith
|
gptkb:cancer
neurodevelopmental disorders
|
|
gptkbp:domain
|
gptkb:protein_tyrosine_phosphatase_domain
PDZ domain
|
|
gptkbp:encodedBy
|
PTPN13 gene
|
|
gptkbp:Entrez_Gene_ID
|
5783
ENSG00000163629
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
gptkb:testis
brain
liver
|
|
gptkbp:fullName
|
Protein Tyrosine Phosphatase, Non-Receptor Type 13
|
|
gptkbp:function
|
signal transduction
regulation of apoptosis
regulation of cell growth
protein tyrosine phosphatase activity
|
|
gptkbp:HGNC_ID
|
9645
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PTPL1
|
|
gptkbp:interactsWith
|
gptkb:14-3-3_proteins
gptkb:Fas_receptor
gptkb:β-catenin
gptkb:IRS1
Rho GTPase
Densin-180
GTPase activating proteins
|
|
gptkbp:locatedOnChromosome
|
4q21
|
|
gptkbp:molecularWeight
|
270 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:autism_spectrum_disorder
tumorigenesis
|
|
gptkbp:numberOfExons
|
53
|
|
gptkbp:OMIM
|
600574
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Danio_rerio
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:phosphataseType
|
non-receptor type
|
|
gptkbp:regulates
|
cell migration
cell adhesion
insulin signaling
apoptosis via Fas pathway
|
|
gptkbp:subcellularLocation
|
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:UniProtID
|
Q12923
|
|
gptkbp:bfsParent
|
gptkb:PTPN13
|
|
gptkbp:bfsLayer
|
7
|