Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:DNA
|
| gptkbp:associated_with |
gptkb:neurodegenerative_diseases
|
| gptkbp:code |
presenilin-1 protein
|
| gptkbp:diseases |
cognitive decline
neurodegeneration |
| gptkbp:function |
gamma-secretase activity
|
| gptkbp:genetic_studies |
causes familial Alzheimer's disease
|
| https://www.w3.org/2000/01/rdf-schema#label |
PSEN1
|
| gptkbp:interacts_with |
gptkb:PSEN2
APP |
| gptkbp:is_expressed_in |
gptkb:Brain
|
| gptkbp:located_in |
chromosome 14
|
| gptkbp:variant |
A246 E
A431 E E280 A G206 A I143 T L286 P L286 V M146 L N141 I R278 I |
| gptkbp:bfsParent |
gptkb:Familial_Alzheimer's_Disease
|
| gptkbp:bfsLayer |
7
|