Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:NCT
Nicastrin precursor protein |
| gptkbp:associatedWith |
gptkb:Alzheimer's_disease
|
| gptkbp:component |
gptkb:gamma-secretase_complex
|
| gptkbp:discoveredBy |
1999
|
| gptkbp:function |
involved in Notch signaling pathway
involved in amyloid precursor protein processing regulates proteolytic activity of gamma-secretase |
| gptkbp:gene |
NCSTN
|
| https://www.w3.org/2000/01/rdf-schema#label |
Nicastrin
|
| gptkbp:interactsWith |
gptkb:APH-1
gptkb:PEN-2 Presenilin-1 |
| gptkbp:locatedIn |
gptkb:human_chromosome_1
|
| gptkbp:location |
gptkb:endoplasmic_reticulum
gptkb:cell_membrane |
| gptkbp:molecularWeight |
~75 kDa
|
| gptkbp:orthologInMouse |
Nicastrin (mouse)
|
| gptkbp:postTranslationalModification |
glycosylation
|
| gptkbp:UniProtID |
Q92542
|
| gptkbp:bfsParent |
gptkb:PSEN1
|
| gptkbp:bfsLayer |
8
|