|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
SAP90
Synapse-associated protein 90
|
|
gptkbp:discoveredIn
|
1992
|
|
gptkbp:domain
|
SH3 domain
PDZ domain
GK domain
|
|
gptkbp:encodedBy
|
DLG4 gene
|
|
gptkbp:expressedIn
|
brain
central nervous system
|
|
gptkbp:foundIn
|
postsynaptic density
|
|
gptkbp:fullName
|
Postsynaptic density protein 95
|
|
gptkbp:function
|
scaffolding protein
synaptic signaling
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PSD-95
|
|
gptkbp:interactsWith
|
gptkb:AMPA_receptor
gptkb:NMDA_receptor
neurexin
neuroligin
|
|
gptkbp:locatedIn
|
neurons
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_17p13.1
|
|
gptkbp:memberOf
|
gptkb:MAGUK_family
|
|
gptkbp:molecularWeight
|
~95 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:autism_spectrum_disorder
schizophrenia
neurodevelopmental disorders
|
|
gptkbp:OMIM
|
602887
|
|
gptkbp:phosphorylates
|
Ser295
Ser561
|
|
gptkbp:regulates
|
synaptic strength
receptor clustering
|
|
gptkbp:role
|
gptkb:synaptic_plasticity
learning and memory
|
|
gptkbp:species
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:UniProtID
|
P78352
|
|
gptkbp:bfsParent
|
gptkb:SHANK3_gene
|
|
gptkbp:bfsLayer
|
7
|