PP2A

GPTKB entity

Statements (27)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:component heterotrimeric holoenzyme
gptkbp:dysregulationAssociatedWith gptkb:cancer
neurodegenerative diseases
gptkbp:EC_number 3.1.3.16
gptkbp:encodedBy gptkb:PPP2CA_gene
gptkb:PPP2CB_gene
gptkbp:foundIn eukaryotic cells
gptkbp:fullName gptkb:Protein_Phosphatase_2A
gptkbp:function serine/threonine phosphatase
https://www.w3.org/2000/01/rdf-schema#label PP2A
gptkbp:involvedIn apoptosis
signal transduction
cell cycle regulation
gptkbp:molecularWeight ~65 kDa (catalytic subunit)
gptkbp:regulates gptkb:MAPK_signaling_pathway
gptkb:Wnt_signaling_pathway
metabolism
cell growth
DNA replication
gptkbp:subunit catalytic subunit (C subunit)
regulatory subunit (B subunit)
structural subunit (A subunit)
gptkbp:target gptkb:microcystin-LR
gptkb:okadaic_acid
gptkbp:bfsParent gptkb:RAF1
gptkbp:bfsLayer 6