Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
heptapeptide
cyanotoxin |
| gptkbp:affects |
animals
humans aquatic life |
| gptkbp:CASNumber |
101043-37-2
|
| gptkbp:category |
environmental pollutant
cyclic peptide toxin |
| gptkbp:cause |
liver damage
gastrointestinal symptoms potential carcinogenicity |
| gptkbp:chemicalFormula |
C49H74N10O12
|
| gptkbp:color |
white powder (pure form)
|
| gptkbp:degradedBy |
gptkb:chlorine
ozone UV light |
| gptkbp:detects |
gptkb:ELISA
gptkb:HPLC |
| gptkbp:firstDescribed |
1980s
|
| gptkbp:foundIn |
algal blooms
freshwater |
| https://www.w3.org/2000/01/rdf-schema#label |
microcystin-LR
|
| gptkbp:IUPACName |
(3S,6S,9S,12S,15S,18S,21S)-3,6,9,12,18,21-hexamethyl-15-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclodocosane-22-carboxylic acid
|
| gptkbp:LD50 |
50 µg/kg (mouse, intraperitoneal)
|
| gptkbp:mechanismOfAction |
inhibits protein phosphatases 1 and 2A
|
| gptkbp:molecularWeight |
994.17 g/mol
|
| gptkbp:monitors |
gptkb:EPA
gptkb:WHO local water authorities |
| gptkbp:namedAfter |
leucine (L) and arginine (R) amino acids
|
| gptkbp:producedBy |
gptkb:Anabaena
Microcystis aeruginosa Planktothrix |
| gptkbp:regulates |
gptkb:World_Health_Organization
|
| gptkbp:removes |
chlorination
ozonation activated carbon filtration advanced oxidation |
| gptkbp:riskFactor |
hepatotoxicity
tumor promotion |
| gptkbp:routeOfExposure |
inhalation
ingestion skin contact |
| gptkbp:solubility |
water soluble
|
| gptkbp:stable |
stable in water
|
| gptkbp:toxicity |
liver
highly toxic |
| gptkbp:WHOguideline |
1 µg/L in drinking water
|
| gptkbp:bfsParent |
gptkb:PP2A
|
| gptkbp:bfsLayer |
7
|