PPP2CB gene

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alias PP2A-beta
PP2Ac-beta
gptkbp:alternativeSplicing yes
gptkbp:associatedWith Alzheimer's disease (potential association)
gptkbp:biologicalProcess signal transduction
cell cycle regulation
apoptosis regulation
protein serine/threonine phosphatase activity
gptkbp:discoveredBy 1990s
gptkbp:encodes Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
gptkbp:Entrez_Gene_ID 5516
ENSG00000100320
gptkbp:expressedIn various tissues including brain, heart, and liver
gptkbp:function catalytic subunit of protein phosphatase 2A
involved in negative control of cell growth and division
gptkbp:geneType protein-coding
gptkbp:HGNC_ID HGNC:9326
https://www.w3.org/2000/01/rdf-schema#label PPP2CB gene
gptkbp:locatedOnChromosome chromosome 8
8q13.1
gptkbp:OMIM 176915
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse Ppp2cb
gptkbp:proteinFamily PPP phosphatase family
gptkbp:UniProtID P62714
gptkbp:bfsParent gptkb:PP2A
gptkbp:bfsLayer 7