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gptkbp:instanceOf
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gptkb:enzyme
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gptkbp:abbreviation
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gptkb:PP2A
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gptkbp:activityRegulatedBy
|
phosphorylation
methylation
interaction with regulatory subunits
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gptkbp:associatedWith
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gptkb:Alzheimer's_disease
gptkb:cancer
|
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gptkbp:biologicalProcess
|
protein serine/threonine phosphatase activity
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gptkbp:component
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cell signaling pathways
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gptkbp:discoveredBy
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gptkb:Edmond_H._Fischer
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gptkbp:EC_number
|
3.1.3.16
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gptkbp:foundIn
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eukaryotes
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gptkbp:function
|
dephosphorylation of serine/threonine residues
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gptkbp:gene
|
PPP2CA
PPP2CB
PPP2R1A
PPP2R1B
PPP2R2A
PPP2R2B
PPP2R2C
PPP2R2D
PPP2R3A
PPP2R3B
PPP2R3C
PPP2R3D
PPP2R5A
PPP2R5B
PPP2R5C
PPP2R5D
PPP2R5E
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gptkbp:GO_term
|
GO:0004721
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Protein Phosphatase 2A
|
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gptkbp:inhibitedBy
|
gptkb:microcystin-LR
gptkb:okadaic_acid
|
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gptkbp:locale
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gptkb:nucleus
gptkb:cytoplasm
|
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gptkbp:orthologIn
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gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae
gptkb:Homo_sapiens
gptkb:Drosophila_melanogaster
|
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gptkbp:regulates
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apoptosis
metabolism
cell division
cell growth
|
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gptkbp:structure
|
heterotrimeric
|
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gptkbp:subunit
|
catalytic subunit (C subunit)
regulatory subunit (B subunit)
scaffolding subunit (A subunit)
|
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gptkbp:UniProtID
|
P62714
P67775
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gptkbp:bfsParent
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gptkb:PP2A
|
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gptkbp:bfsLayer
|
7
|