|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CD273
gptkb:B7-DC
|
|
gptkbp:binds
|
gptkb:PD-1
|
|
gptkbp:discoveredBy
|
gptkb:Lieping_Chen
|
|
gptkbp:discoveredIn
|
2001
|
|
gptkbp:encodedBy
|
gptkb:PDCD1LG2_gene
|
|
gptkbp:Entrez_Gene_ID
|
80380
ENSG00000197646
|
|
gptkbp:expressedIn
|
dendritic cells
macrophages
some tumor cells
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:fullName
|
Programmed cell death 1 ligand 2
|
|
gptkbp:function
|
immune checkpoint protein
|
|
gptkbp:HGNC_ID
|
HGNC:18794
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PD-L2
|
|
gptkbp:involvedIn
|
gptkb:cancer
autoimmune diseases
chronic infections
|
|
gptkbp:locatedOnChromosome
|
chromosome 9p24.1
|
|
gptkbp:memberOf
|
gptkb:B7_family
|
|
gptkbp:modulatedBy
|
immune response
T cell activation
|
|
gptkbp:OMIM
|
605764
|
|
gptkbp:relatedTo
|
PD-L1
PD-1/PD-L1 pathway
|
|
gptkbp:role
|
cancer immune evasion
immune tolerance
regulation of T cell function
|
|
gptkbp:structureType
|
type I transmembrane protein
|
|
gptkbp:target
|
immunotherapy
|
|
gptkbp:UniProtID
|
Q9BQ51
|
|
gptkbp:bfsParent
|
gptkb:programmed_cell_death_protein_1_(PD-1)
|
|
gptkbp:bfsLayer
|
6
|