Statements (41)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
phospholipids
diacylglycerol calcium (for some isoforms) |
| gptkbp:class |
atypical PKCs (aPKC)
conventional PKCs (cPKC) novel PKCs (nPKC) |
| gptkbp:discoveredBy |
gptkb:Yasutomi_Nishizuka
|
| gptkbp:discoveredIn |
1977
|
| gptkbp:foundIn |
eukaryotic cells
|
| gptkbp:function |
signal transduction
phosphorylation of target proteins |
| https://www.w3.org/2000/01/rdf-schema#label |
PKC isoforms
|
| gptkbp:includes |
gptkb:PKC_alpha
gptkb:PKC_beta gptkb:PKC_delta gptkb:PKC_epsilon gptkb:PKC_eta gptkb:PKC_gamma gptkb:PKC_theta gptkb:PKC_zeta PKC iota/lambda |
| gptkbp:proteinFamily |
gptkb:PRKCA
gptkb:PRKCB gptkb:PRKCD gptkb:PRKCE gptkb:PRKCG gptkb:PRKCH gptkb:PRKCI gptkb:PRKCQ gptkb:PRKCZ |
| gptkbp:role |
apoptosis
cell proliferation differentiation immune response neuronal signaling cardiovascular regulation tumor promotion |
| gptkbp:subclassOf |
gptkb:protein_kinase_C
|
| gptkbp:bfsParent |
gptkb:PDPK1
|
| gptkbp:bfsLayer |
7
|