|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:G6PD_HUMAN
gptkb:G6PDH
|
|
gptkbp:associatedWith
|
gptkb:G6PD_deficiency
|
|
gptkbp:catalyzes
|
D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH
|
|
gptkbp:cofactor
|
NADP+
|
|
gptkbp:Entrez_Gene_ID
|
2539
ENSP00000393585
|
|
gptkbp:enzymeCommissionNumber
|
1.1.1.49
|
|
gptkbp:function
|
catalyzes the first step in the pentose phosphate pathway
|
|
gptkbp:gene
|
gptkb:G6PD
|
|
gptkbp:HGNC_ID
|
4057
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P21399
|
|
gptkbp:InterPro
|
gptkb:IPR006424
IPR001282
IPR006425
|
|
gptkbp:KEGGID
|
hsa:2539
|
|
gptkbp:length
|
515 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:Xq28
X
|
|
gptkbp:molecularWeight
|
59 kDa
|
|
gptkbp:OMIM
|
305900
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
gptkb:pentose_phosphate_pathway
|
|
gptkbp:PDB
|
gptkb:2BHL
2BH9
2E9G
2E9K
2E9L
2E9M
2E9N
2E9O
2E9P
2E9Q
2E9R
2E9S
2E9T
2E9U
2E9V
2E9W
2E9X
2E9Y
2E9Z
|
|
gptkbp:protein_name
|
gptkb:Glucose-6-phosphate_1-dehydrogenase
|
|
gptkbp:proteinFamily
|
PF00479
PF02781
|
|
gptkbp:Reactome
|
R-HSA-71336
|
|
gptkbp:RefSeq
|
NP_000393.4
|
|
gptkbp:sequenceStatus
|
complete
|
|
gptkbp:structure
|
homodimer or homotetramer
|
|
gptkbp:subcellularLocation
|
gptkb:cytoplasm
|
|
gptkbp:tissue_specificity
|
ubiquitous
|
|
gptkbp:UniGene
|
Hs.654
|
|
gptkbp:UniProtID
|
gptkb:P21399
|
|
gptkbp:bfsParent
|
gptkb:Aconitase
|
|
gptkbp:bfsLayer
|
7
|