Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
aconitate hydratase
citrate hydro-lyase |
| gptkbp:catalyzes |
isomerization of citrate to isocitrate
|
| gptkbp:contains |
iron-sulfur cluster
|
| gptkbp:discoveredBy |
gptkb:Albert_Szent-Györgyi
|
| gptkbp:EC_number |
4.2.1.3
|
| gptkbp:foundIn |
mitochondria
cytosol |
| gptkbp:gene |
gptkb:ACO1
gptkb:ACO2 |
| gptkbp:has_cofactor |
[4Fe-4S] cluster
|
| gptkbp:has_molecular_function |
aconitate hydratase activity
|
| gptkbp:hasRole |
iron homeostasis
|
| https://www.w3.org/2000/01/rdf-schema#label |
Aconitase
|
| gptkbp:inhibitedBy |
nitric oxide
fluoroacetate |
| gptkbp:involves |
citric acid cycle
|
| gptkbp:presentIn |
gptkb:Bacteria
animals plants |
| gptkbp:regulates |
iron-responsive element (IRE) binding
|
| gptkbp:sensitivity |
oxidative stress
|
| gptkbp:structure |
X-ray crystallography
|
| gptkbp:UniProt_ID_(human_ACO1) |
gptkb:P21399
|
| gptkbp:UniProt_ID_(human_ACO2) |
gptkb:Q99798
|
| gptkbp:bfsParent |
gptkb:Enzymes
|
| gptkbp:bfsLayer |
6
|