|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
NADP+
|
|
gptkbp:alternativeSplicing
|
no
|
|
gptkbp:associatedWith
|
gptkb:G6PD_deficiency
gptkb:anemia
|
|
gptkbp:clinicalTrialPhase
|
G6PD activity assay
|
|
gptkbp:cofactor
|
NADP+
|
|
gptkbp:database
|
gptkb:GeneCards
gptkb:HGNC
gptkb:OMIM
gptkb:UniProt
gptkb:Ensembl
gptkb:Reactome
gptkb:KEGG
|
|
gptkbp:Entrez_Gene_ID
|
2539
|
|
gptkbp:enzymeCommissionNumber
|
1.1.1.49
|
|
gptkbp:evidence
|
protein level
|
|
gptkbp:expressedIn
|
high in red blood cells
present in all tissues
|
|
gptkbp:fullName
|
gptkb:Glucose-6-phosphate_1-dehydrogenase
|
|
gptkbp:function
|
catalyzes the first step in the pentose phosphate pathway
oxidizes glucose-6-phosphate to 6-phosphoglucono-δ-lactone
|
|
gptkbp:gene
|
gptkb:G6PD
|
|
gptkbp:GO_term
|
GO:0006098
GO:0004345
GO:0055114
|
|
gptkbp:hasIsoform
|
canonical
|
|
gptkbp:hasPolymorphism
|
highly polymorphic
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
G6PD HUMAN
|
|
gptkbp:inhibitedBy
|
polydatin
dehydroepiandrosterone
|
|
gptkbp:length
|
515 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:Xq28
|
|
gptkbp:molecularWeight
|
59 kDa
|
|
gptkbp:mutationAssociatedWith
|
can cause favism
can cause neonatal jaundice
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
G6pd (mouse)
G6pd (rat)
|
|
gptkbp:pathway
|
gptkb:pentose_phosphate_pathway
|
|
gptkbp:PDB
|
2BH9
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
|
|
gptkbp:RefSeq
|
NP_000393.4
|
|
gptkbp:reviewedBy
|
yes
|
|
gptkbp:sequenceStatus
|
complete
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:subcellularLocation
|
gptkb:cytoplasm
|
|
gptkbp:tissue_specificity
|
ubiquitous
|
|
gptkbp:UniProtID
|
P11413
|
|
gptkbp:bfsParent
|
gptkb:P37023
|
|
gptkbp:bfsLayer
|
7
|