|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:APO-1
gptkb:CD95
gptkb:TNFRSF6
gptkb:Fas_cell_surface_death_receptor
|
|
gptkbp:antigen
|
gptkb:CD95
|
|
gptkbp:associatedWith
|
gptkb:Systemic_lupus_erythematosus
Autoimmune lymphoproliferative syndrome
|
|
gptkbp:biologicalProcess
|
apoptotic process
receptor activity
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:disulfideBond
|
present
|
|
gptkbp:domain
|
death domain
TNFR/NGFR cysteine-rich domain
|
|
gptkbp:encodedBy
|
gptkb:FAS_gene
|
|
gptkbp:Entrez_Gene_ID
|
355
ENSP00000379410
|
|
gptkbp:family
|
gptkb:tumor_necrosis_factor_receptor_superfamily
|
|
gptkbp:function
|
induces apoptosis
|
|
gptkbp:GO_term
|
GO:0006915 (apoptotic process)
GO:0005031 (tumor necrosis factor-activated receptor activity)
|
|
gptkbp:hasIsoform
|
multiple isoforms
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:11920
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P15529
|
|
gptkbp:interactsWith
|
gptkb:FADD
gptkb:CASP8
gptkb:TRADD
|
|
gptkbp:length
|
335 amino acids
|
|
gptkbp:locatedOnChromosome
|
10q23
|
|
gptkbp:mass
|
37,274 Da
|
|
gptkbp:OMIM
|
134637
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Fas protein
rat Fas protein
|
|
gptkbp:partOf
|
extrinsic apoptotic signaling pathway
|
|
gptkbp:pathway
|
Apoptosis
Immune system
|
|
gptkbp:PDB
|
1DDF
3EZQ
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:RefSeq
|
NP_000034.1
|
|
gptkbp:reviewedBy
|
yes
|
|
gptkbp:sequenceStatus
|
complete
|
|
gptkbp:signalPeptide
|
present
|
|
gptkbp:structure
|
single-pass type I membrane protein
|
|
gptkbp:subunit
|
homotrimer
|
|
gptkbp:tissue_specificity
|
widely expressed
|
|
gptkbp:transmembraneDomains
|
present
|
|
gptkbp:UniProt_entry_name
|
TNR6_HUMAN
|
|
gptkbp:UniProtID
|
gptkb:P15529
|
|
gptkbp:bfsParent
|
gptkb:CD46
|
|
gptkbp:bfsLayer
|
8
|