Fas cell surface death receptor
GPTKB entity
Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
gptkbp:alsoKnownAs |
gptkb:APO-1
gptkb:CD95 gptkb:TNFRSF6 |
gptkbp:associatedWith |
gptkb:autoimmune_lymphoproliferative_syndrome
|
gptkbp:component |
gptkb:plasma_membrane
|
gptkbp:discoveredIn |
1991
|
gptkbp:domain |
death domain
|
gptkbp:encodedBy |
gptkb:FAS_gene
|
gptkbp:expressedIn |
immune cells
|
gptkbp:foundIn |
gptkb:Homo_sapiens
|
gptkbp:function |
receptor activity
induces apoptosis |
gptkbp:GOProcess |
apoptotic process
|
https://www.w3.org/2000/01/rdf-schema#label |
Fas cell surface death receptor
|
gptkbp:involvedIn |
programmed cell death
immune regulation |
gptkbp:ligand |
gptkb:Fas_ligand_(FasL)
|
gptkbp:locatedOnChromosome |
gptkb:10q23.31
|
gptkbp:memberOf |
gptkb:tumor_necrosis_factor_receptor_superfamily
|
gptkbp:mutationAssociatedWith |
autoimmune disorders
|
gptkbp:OMIM |
134637
|
gptkbp:orthologIn |
gptkb:Mus_musculus
|
gptkbp:structure |
transmembrane protein
|
gptkbp:UniProtID |
gptkb:P25445
|
gptkbp:bfsParent |
gptkb:FAS_gene
|
gptkbp:bfsLayer |
7
|