|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
Bcl-2-like protein 4
Bcl2-L-4
Bcl2-associated X protein
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:biologicalProcess
|
protein heterodimerization activity
regulation of apoptotic process
|
|
gptkbp:cellularComponent
|
mitochondrial outer membrane
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:Entrez_Gene_ID
|
ENSP00000226218
|
|
gptkbp:enzymeCommissionNumber
|
none
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:family
|
gptkb:Bcl-2_family
|
|
gptkbp:function
|
promotes apoptosis
|
|
gptkbp:gene
|
gptkb:BAX
|
|
gptkbp:hasIsoform
|
BAX alpha
BAX beta
BAX delta
|
|
gptkbp:hasTranscriptVariant
|
NM_004324.3
NM_138761.4
NM_138763.3
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:959
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
O14745
|
|
gptkbp:interactsWith
|
gptkb:MCL1
gptkb:BAK1
gptkb:BCL2
gptkb:BCL2L1
|
|
gptkbp:length
|
192 amino acids
|
|
gptkbp:locatedOnChromosome
|
19q13.33
|
|
gptkbp:molecularWeight
|
21,104 Da
|
|
gptkbp:mutationAssociatedWith
|
loss of function reduces apoptosis
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Bax
rat Bax
|
|
gptkbp:PDB
|
gptkb:1F16
4S0O
6F46
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:protein_name
|
Apoptosis regulator BAX
|
|
gptkbp:RefSeq
|
NP_620116.1
|
|
gptkbp:relatedTo
|
apoptosis
|
|
gptkbp:reviewedBy
|
yes
|
|
gptkbp:sequenceStatus
|
complete
|
|
gptkbp:subcellularLocation
|
cytosol
mitochondrion
|
|
gptkbp:UniProtID
|
gptkb:O14745
|
|
gptkbp:bfsParent
|
gptkb:SLC9A3R1
|
|
gptkbp:bfsLayer
|
7
|