Nonsteroidal anti-inflammatory drugs
GPTKB entity
Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:abbreviation |
gptkb:NSAIDs
|
| gptkbp:category |
analgesic
anti-inflammatory antipyretic |
| gptkbp:compatibleWith |
gptkb:Corticosteroid
opioid |
| gptkbp:contraindication |
gptkb:peptic_ulcer_disease
chronic kidney disease aspirin allergy |
| gptkbp:discoveredIn |
20th century
|
| gptkbp:drugInteraction |
gptkb:methotrexate
lithium corticosteroids anticoagulants antihypertensives |
| gptkbp:example |
gptkb:diclofenac
gptkb:ibuprofen gptkb:naproxen gptkb:aspirin gptkb:celecoxib indomethacin ketoprofen meloxicam |
| gptkbp:excretion |
kidneys
|
| https://www.w3.org/2000/01/rdf-schema#label |
Nonsteroidal anti-inflammatory drugs
|
| gptkbp:introducedIn |
aspirin in 1899
|
| gptkbp:legalStatus |
over-the-counter
prescription |
| gptkbp:mechanismOfAction |
inhibit cyclooxygenase enzymes
reduce prostaglandin synthesis |
| gptkbp:metabolism |
liver
|
| gptkbp:notEffectiveAgainst |
viral infections
bacterial infections |
| gptkbp:overdoseSymptoms |
renal failure
gastrointestinal bleeding tinnitus |
| gptkbp:pregnancyCategory |
varies by drug
|
| gptkbp:routeOfAdministration |
oral
topical intravenous rectal |
| gptkbp:sideEffect |
ulcer
increased bleeding risk gastrointestinal irritation kidney dysfunction |
| gptkbp:usedFor |
pain relief
fever reduction inflammation reduction |
| gptkbp:bfsParent |
gptkb:NSAIDs
gptkb:Lupus |
| gptkbp:bfsLayer |
6
|