Nonsteroidal anti-inflammatory drugs

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:drug
gptkbp:abbreviation	gptkb:NSAIDs
gptkbp:category	gptkb:analgesic gptkb:antipyretic anti-inflammatory
gptkbp:compatibleWith	gptkb:opioid gptkb:Corticosteroid
gptkbp:contraindication	gptkb:peptic_ulcer_disease chronic kidney disease aspirin allergy
gptkbp:discoveredIn	20th century
gptkbp:drugInteraction	gptkb:methotrexate lithium corticosteroids anticoagulants antihypertensives
gptkbp:example	gptkb:diclofenac gptkb:ibuprofen gptkb:naproxen gptkb:aspirin gptkb:celecoxib indomethacin ketoprofen meloxicam
gptkbp:excretion	kidneys
gptkbp:introducedIn	aspirin in 1899
gptkbp:legalStatus	over-the-counter prescription
gptkbp:mechanismOfAction	inhibit cyclooxygenase enzymes reduce prostaglandin synthesis
gptkbp:metabolism	liver
gptkbp:notEffectiveAgainst	viral infections bacterial infections
gptkbp:overdoseSymptoms	renal failure gastrointestinal bleeding tinnitus
gptkbp:pregnancyCategory	varies by drug
gptkbp:routeOfAdministration	oral topical intravenous rectal
gptkbp:sideEffect	ulcer increased bleeding risk gastrointestinal irritation kidney dysfunction
gptkbp:usedFor	pain relief fever reduction inflammation reduction
gptkbp:bfsParent	gptkb:NSAIDs gptkb:Pain_Killers gptkb:Lupus
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	Nonsteroidal anti-inflammatory drugs