|
gptkbp:instance_of
|
gptkb:drug
|
|
gptkbp:bfsLayer
|
7
|
|
gptkbp:bfsParent
|
gptkb:Celebrex
|
|
gptkbp:approves
|
gptkb:1998
gptkb:FDA
|
|
gptkbp:brand
|
gptkb:Celebrex
|
|
gptkbp:category
|
gptkb:C
|
|
gptkbp:class
|
COX-2 inhibitor
arylpropionic acid derivative
|
|
gptkbp:composed_of
|
via cyclization of 4-(methylsulfonyl)aniline
|
|
gptkbp:contraindication
|
severe heart failure
sulfa allergy
active peptic ulcer
|
|
gptkbp:developed_by
|
gptkb:Pharmacia
|
|
gptkbp:excretion
|
urine
feces
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
celecoxib
|
|
gptkbp:indication
|
gptkb:rheumatoid_arthritis
osteoarthritis
acute pain
dysmenorrhea
|
|
gptkbp:ingredients
|
C17 H17 N3 O2 S
|
|
gptkbp:interacts_with
|
gptkb:methotrexate
gptkb:ACE_inhibitors
gptkb:warfarin
lithium
diuretics
|
|
gptkbp:is_available_on
|
gptkb:beer
gptkb:tablet
|
|
gptkbp:is_used_for
|
pain relief
arthritis treatment
inflammation reduction
|
|
gptkbp:lifespan
|
11 hours
|
|
gptkbp:manager
|
oral
|
|
gptkbp:marketed_as
|
gptkb:Celebrex
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:research
|
gptkb:healthcare_organization
cardiovascular disease prevention
Alzheimer's disease treatment
pain management in cancer patients
preventing colorectal polyps
|
|
gptkbp:side_effect
|
dizziness
headache
nausea
gastrointestinal bleeding
diarrhea
liver damage
cardiovascular events
stomach pain
kidney problems
|
|
gptkbp:type_of
|
169590-42-5
|