Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
nonsteroidal anti-inflammatory drug |
| gptkbp:ATCCode |
gptkb:M01AB05
|
| gptkbp:availableOn |
gptkb:tablet
musical composition injection gel eye drops |
| gptkbp:brand |
gptkb:Voltaren
gptkb:Cataflam gptkb:Zipsor gptkb:Zorvolex |
| gptkbp:CASNumber |
15307-86-5
|
| gptkbp:chemicalFormula |
C14H11Cl2NO2
|
| gptkbp:contraindication |
peptic ulcer
hypersensitivity to NSAIDs severe heart failure |
| gptkbp:discoveredBy |
gptkb:Ciba-Geigy
|
| gptkbp:eliminationHalfLife |
1-2 hours
|
| gptkbp:excretion |
urine
bile |
| https://www.w3.org/2000/01/rdf-schema#label |
diclofenac
|
| gptkbp:introducedIn |
1973
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
COX inhibitor
prostaglandin synthesis inhibitor |
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
C (US)
D (US, third trimester) |
| gptkbp:riskFactor |
gastrointestinal bleeding
renal impairment cardiovascular events |
| gptkbp:routeOfAdministration |
oral
topical intramuscular rectal ophthalmic |
| gptkbp:sideEffect |
nausea
dizziness headache rash elevated liver enzymes gastrointestinal upset |
| gptkbp:usedFor |
pain relief
inflammation reduction treatment of arthritis treatment of ankylosing spondylitis treatment of dysmenorrhea treatment of migraines |
| gptkbp:WHOModelListOfEssentialMedicines |
included
|
| gptkbp:bfsParent |
gptkb:CYP2C9
gptkb:Voltaren |
| gptkbp:bfsLayer |
5
|