|
gptkbp:instanceOf
|
gptkb:nonsteroidal_anti-inflammatory_drug
gptkb:drug
|
|
gptkbp:ATCCode
|
gptkb:M01AB05
|
|
gptkbp:availableOn
|
gptkb:eye_drops
gptkb:musical_composition
gptkb:tablet
injection
gel
|
|
gptkbp:brand
|
gptkb:Voltaren
gptkb:Cataflam
gptkb:Zipsor
gptkb:Zorvolex
|
|
gptkbp:CASNumber
|
15307-86-5
|
|
gptkbp:chemicalFormula
|
C14H11Cl2NO2
|
|
gptkbp:contraindication
|
gptkb:peptic_ulcer
hypersensitivity to NSAIDs
severe heart failure
|
|
gptkbp:discoveredBy
|
gptkb:Ciba-Geigy
|
|
gptkbp:eliminationHalfLife
|
1-2 hours
|
|
gptkbp:excretion
|
urine
bile
|
|
gptkbp:introducedIn
|
1973
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
COX inhibitor
prostaglandin synthesis inhibitor
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
C (US)
D (US, third trimester)
|
|
gptkbp:riskFactor
|
gastrointestinal bleeding
renal impairment
cardiovascular events
|
|
gptkbp:routeOfAdministration
|
oral
topical
intramuscular
rectal
ophthalmic
|
|
gptkbp:sideEffect
|
nausea
dizziness
headache
rash
elevated liver enzymes
gastrointestinal upset
|
|
gptkbp:usedFor
|
pain relief
inflammation reduction
treatment of arthritis
treatment of ankylosing spondylitis
treatment of dysmenorrhea
treatment of migraines
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
included
|
|
gptkbp:bfsParent
|
gptkb:NSAID
gptkb:NSAIDs
gptkb:Voltaren
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
diclofenac
|