Non-Homologous End Joining

GPTKB entity

Statements (38)
Predicate Object
gptkbp:instanceOf DNA repair mechanism
gptkbp:abbreviation NHEJ
gptkbp:activeIn gptkb:S_phase
G1 phase
G2 phase
gptkbp:alternativeTo homologous recombination
gptkbp:cause mutations
deletions
insertions
gptkbp:compatibleWith homologous template
gptkbp:discoveredIn 1990s
gptkbp:errorProne true
gptkbp:foundIn prokaryotes
eukaryotes
https://www.w3.org/2000/01/rdf-schema#label Non-Homologous End Joining
gptkbp:involvesProtein gptkb:DNA-PKcs
gptkb:Ku70
gptkb:Ku80
Ligase IV
XRCC4
XLF
gptkbp:lastStep ligation of DNA ends
gptkbp:numberOfStages DNA end recognition
gptkbp:occurredIn cell cycle
gptkbp:processor double-strand break repair
gptkbp:regulates gptkb:ATM_kinase
gptkb:DNA-PKcs
gptkbp:relatedTo gptkb:V(D)J_recombination
gptkb:CRISPR-Cas9
immunology
cancer biology
genome editing
class switch recombination
gptkbp:studiedIn gptkb:yeast
gptkb:Bacteria
mammals
gptkbp:bfsParent gptkb:Non-Homologous_Recombination
gptkbp:bfsLayer 8