gamma delta T cells

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf T cell subtype
gptkbp:abundantIn gptkb:skin
epithelial tissues
gut mucosa
gptkbp:activatedBy phosphoantigens
butyrophilin molecules
gptkbp:canBe regulatory
pro-inflammatory
gptkbp:canKill tumor cells
infected cells
gptkbp:contributedTo innate immunity
adaptive immunity
gptkbp:developIn gptkb:thymus
gptkbp:distinctFrom alpha beta T cells
gptkbp:doNotRequire MHC presentation
gptkbp:doNotUndergo classical positive and negative selection
gptkbp:expressedIn gptkb:NKG2D
gptkb:CD3
gptkb:TCR_delta_chain
gptkb:TCR_gamma_chain
NK cell markers
gamma delta T cell receptor
gptkbp:firstDescribed 1980s
gptkbp:foundIn vertebrates
gptkbp:function cytotoxicity
cytokine production
immune surveillance
gptkbp:hasSubgroup white blood cells
lymphocytes
https://www.w3.org/2000/01/rdf-schema#label gamma delta T cells
gptkbp:involvedIn wound healing
tissue homeostasis
gptkbp:involves infectious diseases
autoimmune diseases
tumor immunity
gptkbp:mayExpress gptkb:CD4
gptkb:CD8
gptkbp:produces gptkb:interferon-gamma
gptkb:tumor_necrosis_factor_alpha
interleukin-17
gptkbp:proportionOfTCells 1-10% in human peripheral blood
gptkbp:recognizedBy non-peptide antigens
lipid antigens
phosphoantigens
gptkbp:response stress-induced ligands
gptkbp:secretes gptkb:perforin
gptkb:granzyme_B
gptkbp:studiedBy immunotherapy
gptkbp:bfsParent gptkb:interleukin-17A
gptkbp:bfsLayer 6