|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
NKG2DL2
RAET1H
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:virus
|
|
gptkbp:cellularComponent
|
gptkb:cell_membrane
|
|
gptkbp:compatibleWith
|
most normal tissues
|
|
gptkbp:component
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
Cosman et al.
|
|
gptkbp:discoveredIn
|
2001
|
|
gptkbp:encodedBy
|
ULBP2 gene
|
|
gptkbp:Entrez_Gene_ID
|
80330
ENSG00000125398
|
|
gptkbp:expressedIn
|
various tissues
tumor cells
epithelial cells
|
|
gptkbp:fullName
|
UL16 binding protein 2
|
|
gptkbp:function
|
receptor binding
MHC class I protein binding
activates natural killer (NK) cells
activates some T cells
ligand for NKG2D receptor
|
|
gptkbp:gene
|
gptkb:ULBP2
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOProcess
|
immune response
|
|
gptkbp:hasTranscriptVariant
|
ULBP2-201
ULBP2-202
|
|
gptkbp:HGNC_ID
|
HGNC:18460
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ULBP2
|
|
gptkbp:inducedBy
|
gptkb:virus
cellular stress
tumor transformation
|
|
gptkbp:interactsWith
|
gptkb:NKG2D
|
|
gptkbp:length
|
246 amino acids
|
|
gptkbp:locatedOnChromosome
|
6q25.1
|
|
gptkbp:molecularWeight
|
27 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Rae-1
|
|
gptkbp:pathway
|
immune system
innate immune response
NK cell mediated cytotoxicity
|
|
gptkbp:PDB
|
2I4F
|
|
gptkbp:postTranslationalModification
|
glycosylation
|
|
gptkbp:proteinFamily
|
MHC class I-like protein
|
|
gptkbp:relatedTo
|
immune response
|
|
gptkbp:structure
|
gptkb:protein
|
|
gptkbp:UniProtID
|
Q9BZM6
|
|
gptkbp:bfsParent
|
gptkb:NKG2D
|
|
gptkbp:bfsLayer
|
7
|