Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
KARAP
TYROBP |
| gptkbp:contains |
gptkb:immunoreceptor_tyrosine-based_activation_motif_(ITAM)
|
| gptkbp:discoveredIn |
1997
|
| gptkbp:encodedBy |
TYROBP gene
|
| gptkbp:expressedIn |
gptkb:natural_killer_cells
myeloid cells |
| gptkbp:foundIn |
humans
mice |
| gptkbp:function |
adaptor protein in immune signaling
|
| https://www.w3.org/2000/01/rdf-schema#label |
DAP12
|
| gptkbp:interactsWith |
gptkb:TREM2
gptkb:CD94/NKG2C SIRPĪ²1 |
| gptkbp:locale |
gptkb:cell_membrane
|
| gptkbp:locatedOnChromosome |
chromosome 19q13.12
|
| gptkbp:molecularWeight |
~12 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:Nasu-Hakola_disease
polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL) |
| gptkbp:structure |
type I transmembrane protein
|
| gptkbp:bfsParent |
gptkb:NKG2D
gptkb:TREM2 |
| gptkbp:bfsLayer |
7
|