|
gptkbp:instanceOf
|
immune response
lymphocyte
|
|
gptkbp:abbreviation
|
Natural Killer T cells
|
|
gptkbp:activatedBy
|
alpha-galactosylceramide
|
|
gptkbp:canBe
|
anti-inflammatory
pro-inflammatory
|
|
gptkbp:discoveredBy
|
gptkb:Albert_Bendelac
Paul B. Savage
|
|
gptkbp:expressedIn
|
gptkb:T_cell_receptor_(TCR)
NK cell markers
|
|
gptkbp:firstDescribed
|
1995
|
|
gptkbp:foundIn
|
mammals
|
|
gptkbp:fullName
|
Natural Killer T cells
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NKT cells
|
|
gptkbp:involvedIn
|
gptkb:diabetes
gptkb:allergy
asthma
immunotherapy
|
|
gptkbp:location
|
gptkb:thymus
blood
liver
spleen
bone marrow
|
|
gptkbp:marking
|
gptkb:CD56
gptkb:CD3
CD161
invariant TCR alpha chain (Vα24-Jα18 in humans)
|
|
gptkbp:produces
|
gptkb:interferon-gamma
gptkb:interleukin-4
cytokines
|
|
gptkbp:recognizedBy
|
lipid antigens
CD1d molecule
|
|
gptkbp:relatedTo
|
gptkb:MHC_class_I-like_molecules
innate immunity
adaptive immunity
|
|
gptkbp:role
|
autoimmunity
immune regulation
infection response
tumor immunity
|
|
gptkbp:studiedIn
|
immunology
|
|
gptkbp:subspecies
|
gptkb:T_cells
Natural Killer cells
Type I NKT cells
Type II NKT cells
|
|
gptkbp:surfaceMolecule
|
gptkb:TCR
CD1d
NK1.1 (in mice)
|
|
gptkbp:bfsParent
|
gptkb:NKG2D
|
|
gptkbp:bfsLayer
|
7
|