|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:c-Myb
MYB transcription factor
|
|
gptkbp:associatedWith
|
gptkb:acute_myeloid_leukemia
various cancers
|
|
gptkbp:discoveredBy
|
gptkb:Harold_E._Varmus
gptkb:J._Michael_Bishop
|
|
gptkbp:encodes
|
gptkb:Myb_protein
|
|
gptkbp:Entrez_Gene_ID
|
4602
ENSG00000118513
|
|
gptkbp:expressedIn
|
gptkb:testis
gptkb:thymus
bone marrow
colon
|
|
gptkbp:firstDescribed
|
1976
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
regulation of cell proliferation
transcription factor
regulation of differentiation
|
|
gptkbp:gene
|
gptkb:MYB
|
|
gptkbp:HGNC_ID
|
7545
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MYB proto-oncogene
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6
|
|
gptkbp:mutationAssociatedWith
|
oncogenic transformation
|
|
gptkbp:OMIM
|
189990
|
|
gptkbp:orthologIn
|
gptkb:Gallus_gallus
gptkb:Mus_musculus
|
|
gptkbp:proteinFamily
|
DNA-binding domain
transactivation domain
negative regulatory domain
|
|
gptkbp:regulates
|
apoptosis
gene expression
cell cycle
hematopoiesis
|
|
gptkbp:targetGene
|
gptkb:CCNB1
gptkb:GATA3
gptkb:KITLG
gptkb:CDK6
gptkb:BCL2
gptkb:MYC
MIR155HG
MIR17HG
MIR21
MIR223
MIR29B1
|
|
gptkbp:UniProtID
|
P10242
|
|
gptkbp:bfsParent
|
gptkb:MYB_gene
|
|
gptkbp:bfsLayer
|
8
|